Chronic Myeloid Leukemia (CML) Treatment in Pimpri-Chinchwad, Pune

What Is CML?

CML full form in medical terms is Chronic Myeloid Leukemia. It is characterized by an overproduction of white blood cells, specifically myeloid cells. These cells don't mature properly and can interfere with the normal production of other blood cells.

The disease is typically linked to a genetic mutation known as the Philadelphia chromosome, which produces an abnormal gene called BCR-ABL1. This gene instructs cells to make a protein that encourages excessive cell growth.

CML Pathology Outlines and Stages

Understanding the CML pathology outlines helps both doctors and patients identify how far the disease has progressed. CML is typically categorized into three main CML stages:

  1. Chronic Phase: This is the earliest and most manageable stage, where abnormal white blood cells are present but not overwhelming.
  2. Accelerated Phase: The disease progresses faster, and symptoms become more noticeable.
  3. Blast Crisis: This advanced stage resembles acute leukemia, where the number of immature cells (blasts) spikes dangerously.

What Causes CML?

The exact CML causes are not always clear, but in most cases, the condition is associated with a genetic mutation that occurs spontaneously—not inherited. This mutation causes the BCR-ABL gene to form, which results in the production of a protein that leads to uncontrolled cell division.

Environmental factors such as radiation exposure may increase risk, but in most cases, chronic myeloid leukemia causes are unknown and not linked to lifestyle or family history.

Symptoms of CML Disease

In the early stages, CML may not cause noticeable symptoms. However, as the disease progresses, patients may experience:

  • Fatigue or weakness
  • Unexplained weight loss
  • Night sweats
  • Fever
  • Pain or fullness below the ribs due to an enlarged spleen
  • Frequent infections or easy bruising

If you experience these symptoms, consult with chronic lymphocytic leukemia doctors or specialists in hematologic malignancies.

Diagnosing Chronic Myeloid Leukemia

Diagnosing CML often involves:

  • Blood tests to check white blood cell counts
  • Bone marrow biopsy to examine blood-forming cells
  • Genetic testing to identify the Philadelphia chromosome and BCR-ABL gene

These diagnostic tools help determine the chronic myeloid leukemia stages and guide treatment planning.

Chronic Myeloid Leukemia Treatment Options

Thanks to medical advances, chronic myelogenous leukemia treatment has become much more effective in recent years. Here are the most common options:

  1. Targeted Therapy: Targeted therapy drugs, such as tyrosine kinase inhibitors (TKIs), directly block the BCR-ABL protein. These medications include Imatinib, Dasatinib, Nilotinib, Bosutinib, and Ponatinib.
  2. Chemotherapy: While less common today for early-stage CML, chemotherapy may be used when TKIs are ineffective or during the blast crisis phase.
  3. Stem Cell Transplant: This aggressive approach replaces diseased bone marrow with healthy donor cells and may be considered for younger patients or those who don’t respond to targeted therapy.
  4. Supportive Treatments: Medications to manage anemia, infections, or side effects from therapy are often part of a comprehensive treatment plan.

Accessing Chronic Myeloid Leukaemia Treatment in Pune

If you are searching for chronic myeloid leukaemia treatment near me, Pune offers several reputed centers for hematologic care. At Aditya Birla Hospital, our dedicated team offers:

  • Personalized care plans based on disease stage
  • Access to the best chronic myeloid leukaemia treatment in Pune
  • Ongoing monitoring with advanced diagnostic tools
  • Support from skilled hematologists and oncology nurses

Whether you are looking for chronic myeloid leukaemia treatment doctors in Pune or a multidisciplinary oncology team, our facility provides comprehensive, patient-centric care.

Final Thoughts

Managing CML requires the right combination of accurate diagnosis, expert care, and consistent monitoring. For patients seeking the best chronic myeloid leukaemia treatment, Aditya Birla Hospital in Pimpri-Chinchwad offers compassionate, specialized care tailored to each individual’s needs.

Whether you are looking for the best chronic myeloid leukaemia treatment in Pune, chronic myeloid leukemia treatment specialists, or the best oncologist in Pimpri Pune, our oncology team is here to support your journey. As one of the leading Oncology Hospitals in Pimpri-Chinchwad Pune, we are committed to providing holistic, evidence-based care for patients with CML and other blood cancers.

Chronic Myeloid Leukemia Treatment Near You

Looking for Best Chronic Myeloid Leukemia Treatment in Pimpri Chinchwad? Aditya Birla Memorial Hospital offers expert care for CML with a team of experienced hematologists and oncologists. We use advanced diagnostics, targeted drug therapy, and personalized treatment plans to manage the disease effectively. Patients from Hinjewadi, Wakad, Baner, Aundh, Pimple Saudagar, Bhosari, Ravet, Chinchwad Gaon, Tathawade, Nigdi, PCMC, Pimpri, Moshi, and Chakan can access specialized blood cancer care close to home.


Q1. Is CML curable?

Ans: CML is not typically curable with medication alone, but targeted therapies can help patients live long, healthy lives. Stem cell transplant may offer a potential cure in select cases.

Q2. How long can a person live with CML?

Ans: With proper treatment, many people with CML live for decades. The earlier the disease is diagnosed and treated, the better the outlook.

Q3. What are the side effects of CML treatment?

Ans: Common side effects include fatigue, nausea, muscle cramps, and low blood counts. Your doctor will adjust your treatment to minimize discomfort.

Q4. How often should I visit the doctor after diagnosis?

Ans: Regular follow-ups are crucial. You’ll undergo periodic blood tests and possibly bone marrow exams to ensure the disease is under control.

Q5. What is the difference between chronic myeloid leukemia and chronic lymphocytic leukemia?

Ans: CML affects myeloid cells, while chronic lymphocytic leukemia (CLL) affects lymphocytes. Each has different symptoms, treatment, and progression.